Everybody has to handle contusions and bloody noses from time to time. But for individuals with a condition called von Willebrand disease, these things can in some cases be a problem.
Some people with von Willebrand disease never ever even know they have it because the symptoms are so moderate. People with more severe forms of the disease are less most likely to have issues if they get the correct diagnosis and treatment.
What Is Von Willebrand Disease?
When people have von Willebrand disease (vWD for brief) their blood does not clot effectively. That suggests cuts and injuries cannot scab over too, so they bleed longer than normal.
Bleeding is generally a sign that a blood vessel has been cut or torn. Generally, when someone bleeds, small cells in the blood called platelets plug the hole. With the assistance of calcium, vitamin K, and a protein called fibrinogen, the platelets produce a mesh to hold the plug in location and close the injury. As this mesh dries, it solidifies into a scab.
A compound in the blood called von Willebrand element assists platelets adhere to damaged blood vessels. Special proteins called clotting aspects are likewise needed to assist blood clot– von Willebrand aspect includes one of these thickening aspects, called factor VIII.
People with vWD have bleeding problems because the levels of von Willebrand aspect or aspect VIII in their blood are abnormal. In many cases, the elements do not work the way they’re supposed to.
The disease is called after Erik von Willebrand, the doctor who first identified it. It resembles another bleeding condition called hemophilia. Both conditions are unusual. Unlike hemophilia, which usually impacts just guys, both women and guys can have vWD.
The Types of Von Willebrand Disease
There are different sort of vWD:
- In type 1, a person has less von Willebrand consider the blood than typical. This is the most common and mildest kind of the disease. In fact, it might be so moderate that the person never understands he or she has vWD. People with type 1 vWD sometimes have moderate bruising or nosebleeds, and they can bleed a lot with injuries, surgery, or when they have a tooth pulled.
- In type 2, the level of von Willebrand factor in the blood is normal, but it does not work appropriately. This can result in moderate bleeding problems.
- People with type 3 vWD have severe bleeding issues. They have no measurable von Willebrand consider the blood and very low aspect VIII levels.
- In pseudo or platelet-type vWD, the person’s platelets are unusual, making them adhere to von Willebrand factor too well. This causes clotting issues due to low numbers of platelets and levels of von Willebrand factor.
Causes of Von Willebrand Disease in Child?
A congenital disease, von Willebrand disease is passed down from parent to child. If a parent has vWD, a child has a 50% possibility of getting the gene for the condition.
When a child has type 1 or type 2, it normally indicates she or he acquired the gene from one parent. With type 3, the child generally acquires genes for the disease from both parents.
Symptoms of Von Willebrand Disease in Child
Signs of von Willebrand disease can consist of:
- bruising easily
- abnormally heavy periods or other unusual menstrual bleeding in women
- bleeding from the gums, nose, and lining of the intestinal tracts
- prolonged exuding of blood from cuts
- bleeding excessive or for too long after a tooth is pulled or tonsils are eliminated
Moderate cases of von Willebrand disease can be tough to identify. If a doctor believes you have vWD, he or she will examine you and inquire about your case history. Your medical history includes things like your previous health, your household’s health, and any medications you’re taking. The doctor also may send a blood sample to a laboratory for tests.
What to Do
Having von Willebrand disease doesn’t generally indicate huge life modifications. People with more severe vWD need to prevent contact sports like football and hockey, but other sports and activities are normally OKAY.
If somebody with vWD starts bleeding, it’s usually sufficient to put pressure on the area and await the bleeding to eventually stop. For nosebleeds, pinch the soft part of the nose to help stop the bleeding.
Women with vWD who have begun their durations might wish to carry additional pads or perhaps a modification of clothes in case of mishaps. Often, a girl’s doctor may recommend birth control pills to assist manage heavy menstrual bleeding.
If you have vWD, talk with your doctor prior to taking medication for pain or fever. Don’t take aspirin and ibuprofen since they hinder platelet function and can increase the risk of bleeding. It’s typically OKAY to take acetaminophen for pain or fever, because it has no impact on platelet function.
Medicines for vWD
Some people with more major vWD may have to take medications. The most common medication for type 1 von Willebrand disease is called desmopressin. It causes a temporary boost in the von Willebrand factor level in the blood. It can be given up two methods: by injection or by being sniffed into the nose. Desmopressin might also assist some people with type 2 von Willebrand disease.
People with type 3 (and some with type 2) disease need a medicine called Humate-P. It includes both factor VIII and von Willebrand element. Humate-P is injected into a vein. Patients with type 1 also might require a shot of Humate-P in particular situations, like after major surgery or a major accident.
Other medications, like Amicar, control bleeding by keeping embolism from breaking down too rapidly.
The majority of the time, people with von Willebrand disease can do everything their buddies do. Mentioning buddies, if you have vWD, it doesn’t injured to let the people in your life (like buddies, teammates, or coaches) know that you have it. Von Willebrand disease isn’t contagious– you cannot offer it to anybody– and it can assist to know somebody has your back.