Trisomy 13 or Patau syndrome is a genetic disorder in children with 3 copies of the hereditary material in the thirteenth chromosome. While healthy children have two copies of hereditary material in the thirteenth chromosome. The problem can influence the development of the baby in numerous ways. Keep checking out to find out more about factors that may affect life span in this condition.
Trisomy 13 Life span
While the condition is rather rare, you can still discover babies born with it. The disorder can cause serious mental and physical irregularities consisting of heart flaws. Numerous babies with Patau syndrome are stillborn or pass away within the first few days after being born. It is hard to predict the life expectancy if the baby does not have any instant life-threatening issues.
- About 50% of infants die within the first week of their birth.
- 90% die within a year.
- Only 5-10 % handle to live longer than a year.
Is There Any Treatment for Trisomy 13?
Sadly, there is no conventional treatment offered for infants born with this condition. It is therefore challenging to improve Trisomy 13 life span. Doctor focus their treatment on improving symptoms just. Many children with this condition eventually require surgery in addition to occupational therapy, speech therapy, physical therapy, and other helpful treatment procedures.
Some babies born with incurable abnormality, but some respond well to treatment used to correct structural abnormalities. Unique solutions, methods, and positions are used to deal with feeding problems. The placement of a stomach tube may assist in this regard. Surgery is the only treatment option to correct structural abnormalities such as cleft taste buds and cleft lip. The combination of listening device, special diets, and vision helps may help handle other symptoms of Patau syndrome.
Causes and Symptoms of Trisomy 13
While Trisomy 13 is a congenital disease, it does not pass from the parents to the child. It primarily happens due to defects in the sperm or the egg that forms the fetus. Under normal situations, egg and sperm join and form 23 pairs of chromosomes. In rare cases, egg and sperm form an additional chromosome and the chromosome 13 is launched to the embryo. Both mother’s egg cell and dad’s sperm cell can consider that additional chromosome to the embryo.
There are three types of this condition, and these types also have some impact on the overall Trisomy 13 life expectancy.
- Full Trisomy: In this condition, every cell in the body of an affected baby has an additional copy of chromosome 13.
- Partial Trisomy: In this condition, patients do not have a full additional copy of chromosome 13, and only an additional part of the chromosome attached to some other chromosome in the cells.
- Mosaic: Patients with this kind of condition have an entire extra copy of chromosome 13, but they are not present in a few of the body’s cells.
The symptoms normally depend upon the intensity of the condition. In addition, the symptoms might be various when only some of the cells are affected– it suggests the kind of Trisomy 13 will likewise have an impact on how severe the symptoms are.
The most typical symptoms include cleft palate, close-set eyes, cleft lip, clenched hands, extra fingers, damaged muscle tone, low-set ears, hernia, skeletal defects, damaged mental advancement, and seizure. Some patients may likewise have a small lower jaw, little head, and un-descended testicles.
How Is Trisomy 13 Identified?
A physical exam is usually all that is needed to detect Trisomy 13. An afflicted baby will have specific physical characteristics and symptoms as discussed already, that makes it simple for doctor to identify. Still, they may purchase a blood test to evaluate the chromosomes to confirm the existence of chromosome 13.
It is likewise possible to analyze cells in the amniotic fluid to confirm the existence of chromosomal irregularities. The fluid is generally obtained from the placenta through chorionic villus sampling (CVS). An in-depth fetal ultrasound might likewise help make a diagnosis, but it is not a really reputable way. A chromosome analysis is normally 99.9% precise.
How Typically Does Trisomy 13 Occur?
It is rather a rare disorder and influences only 1 in 16,000 babies in the United States. The risk of having a baby with this condition increases with the age of mom, but a female can give birth to a baby with Trisomy 13 at any age.